Postdoctoral Fellow
Job Description
Full job description
Position Details
Position Information
Recruitment/Posting Title
Postdoctoral Fellow
Job Category
Staff & Executive - Research (Laboratory/Non-Laboratory)
Department
RWJ-Neuro & Cell Biology-PISC
Overview
New Jersey’s academic health center, Rutgers Biomedical and Health Sciences (RBHS) takes an integrated approach to educating students, providing clinical care, and conducting research, all with the goal of improving human health. Aligned with Rutgers University–New Brunswick and collaborating university wide, RBHS includes eight schools, a behavioral health network, and six centers and institutes that focus on cancer treatment and research, neuroscience, clinical and translational research, advanced biotechnology and medicine, environmental and occupational health, and health care policy and aging research.
Our faculty are teachers, clinicians, and scientists with unparalleled experience who advance medical innovation and provide patient care informed by the latest research findings. We offer an outstanding education in medicine, dentistry, pharmacy, public health, nursing, biomedical research, and the full spectrum of allied health careers.
Our clinical and academic facilities are located throughout the state including New Brunswick, Piscataway, Newark, Scotch Plains, Somerset, Blackwood, and other locations. Clinical partners include Robert Wood Johnson University Hospital in New Brunswick, University Hospital in Newark, and other affiliates.
Through this community of healers, scientists, and scholars, Rutgers is equipped as never before to transform lives.
Our faculty are teachers, clinicians, and scientists with unparalleled experience who advance medical innovation and provide patient care informed by the latest research findings. We offer an outstanding education in medicine, dentistry, pharmacy, public health, nursing, biomedical research, and the full spectrum of allied health careers.
Our clinical and academic facilities are located throughout the state including New Brunswick, Piscataway, Newark, Scotch Plains, Somerset, Blackwood, and other locations. Clinical partners include Robert Wood Johnson University Hospital in New Brunswick, University Hospital in Newark, and other affiliates.
Through this community of healers, scientists, and scholars, Rutgers is equipped as never before to transform lives.
Posting Summary
Rutgers, The State University of New Jersey, is seeking a Postdoctoral Fellow for the department of Neuroscience & Cell Biology at the Robert Wood Johnson Medical School.
Applications are invited for motivated scholars with a strong background in lysosomal biology or cell biology to join the laboratory of Pingyue Pan at the Department of Neuroscience and Cell Biology in Rutgers University – Robert Wood Johnson Medical School. The primary research interest in the lab is to understand dopaminergic signaling and its dysregulation in Parkinson’s disease and substance use disorder. Currently, we are investigating the Synj1 gene, which is linked to multiple dopamine related illnesses, including Parkinsonism. In our recent study, we found altered lysosomal parameters and abnormal autolysosomal function in the Synj1 haploinsufficient mouse. Dysfunctional endolysosomal system is highly implicated in the pathogenesis of PD, however, it remains to be investigated whether and how PD associated Synj1 mutation influences the autolysosomal system leading to neurodegeneration. This question will be addressed using novel transgenic mouse models with dopamine neuron specific deletion of Synj1. We employ primary dopamine neuron cultures from transgenic mouse models combined with quantitative imaging, biochemical and behavioral analyses to understand these mechanisms. The position is funded by the NIH R01 grant and startup funds.
Among the key duties of this position are the following:
Applications are invited for motivated scholars with a strong background in lysosomal biology or cell biology to join the laboratory of Pingyue Pan at the Department of Neuroscience and Cell Biology in Rutgers University – Robert Wood Johnson Medical School. The primary research interest in the lab is to understand dopaminergic signaling and its dysregulation in Parkinson’s disease and substance use disorder. Currently, we are investigating the Synj1 gene, which is linked to multiple dopamine related illnesses, including Parkinsonism. In our recent study, we found altered lysosomal parameters and abnormal autolysosomal function in the Synj1 haploinsufficient mouse. Dysfunctional endolysosomal system is highly implicated in the pathogenesis of PD, however, it remains to be investigated whether and how PD associated Synj1 mutation influences the autolysosomal system leading to neurodegeneration. This question will be addressed using novel transgenic mouse models with dopamine neuron specific deletion of Synj1. We employ primary dopamine neuron cultures from transgenic mouse models combined with quantitative imaging, biochemical and behavioral analyses to understand these mechanisms. The position is funded by the NIH R01 grant and startup funds.
Among the key duties of this position are the following:
- Design and lead the project as directed by the supervisor.
- Engages in frequent scientific communication with your supervisor/mentor.
- Perform cell culture, live cell imaging, molecular cloning, biochemical assays, brain pathology analysis, behavioral assessment, data analysis and presentation.
- Assist in maintenance of transgenic mice lines in the vivarium. This involves handling mice for breeding, tail snipping, ear marking and PCR-genotyping.
- Participate in the evaluation of the existing procedures, suggesting revisions and designing new procedures where necessary. Participate in the development of new protocols, procedures, and cell lines in the lab.
- Contribute to the development of performance standards, selection of methodology and instrumentation and coordination of the analytical, biochemical, physiology and instrumentation functions with the research areas to ensure conformance with the goals and objectives of the department. As required, assists in the implementation of the programs and projects in special areas of interest to the department.
- Maintain accurate records of laboratory notebooks and research activity.
Position Status
Full Time
Hours Per Week
Daily Work Shift
Day
Work Arrangement
This position requires a fully on-site work arrangement.
FLSA
Exempt
Grade
99S
Position Salary
$61,805/annual
Annual Minimum Salary
0.000
Annual Mid Range Salary
0.000
Annual Maximum Salary
0.000
Standard Hours
37.50
Union Description
AAUP
Payroll Designation
PeopleSoft
Benefits
Rutgers offers a comprehensive benefit program to eligible employees. For details, please go to http://uhr.rutgers.edu/benefits/benefits-overview.
Seniority Unit
Terms of Appointment
Staff - 12 month
Position Pension Eligibility
ABP
Qualifications
Minimum Education and Experience
- PhD degree required in neurobiology, biomedical sciences or similar, passion for scientific discovery, research experiences in lysosome biology.
- The ideal candidate has at least one (1) published first author paper in a reputable journal.
Certifications/Licenses
Required Knowledge, Skills, and Abilities
- A detail-oriented and quantitative mind is greatly appreciated.
Preferred Qualifications
Equipment Utilized
- Equipment specific to a N&CB laboratory.
Physical Demands and Work Environment
- Physical Demands: Standing, sitting, walking, talking or hearing. No special vision requirements.
- Work Environment: Radioactivity is used in the laboratory. Lab environment; moderate noise.
Special Conditions
Posting Details
Posting Number
24ST1612
Posting Open Date
Special Instructions to Applicants
Regional Campus
Rutgers Biomedical and Health Sciences (RBHS)
Home Location Campus
Piscataway (RBHS)
City
Piscataway
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